Julia R Migliore
You may have heard of Cas9 before in discussions and news about gene editing with CRISPR! (The two women who established how to use CRISPR-Cas9 in the lab won the 2020 Nobel Prize in Chemistry.) In nature, CRISPR is a bacterial acquired immune system. It recognizes invading DNA, like from viruses for example, and "saves" …
DNA Polymerase lives and works in the cell's nucleus where it is the star of DNA replication. In the cell nucleus, DNA Polymerase makes a copy of DNA to prepare for cell division. When a cell divides into two cells, it needs to make a copy of its DNA so that each resulting cell has …
E Cadherin is a membrane protein that helps cells stick to other cells at cell junctions. Cell junctions are critical for forming and maintaining healthy tissues. Could you imagine if your skin cells suddenly couldn't stick together?! E Cadherin is one of the proteins that makes sure our skin, and every other part of our …
This blog is all about proteins, but what even is a protein? Think about how you would define "protein" for a moment. Feel free to comment and share your definition. Now that it's in the open, throw it in the garbage. If you ask Google to "define protein," this is what you will find: "Pro•tein …
Continue reading "What is a protein?? (P.S. science is for you)"
ATP synthase is a really, really important protein for life. That's because it makes ATP molecules, which are like the energy currency of the molecular world. (Essentially, ATP = Energy!) As you may expect, ATP synthase works in the inner membranes of mitochondria. If mitochondria are the powerhouses of the cell, ATP synthase is the …
Its name is pronounced "sodium-potassium A. T. P. ay-ss" but it more commonly goes by "sodium-potassium pump" or "Na+/K+ pump." It works at the cell membrane and is named for its job: pumping sodium and potassium ions using energy from ATP. Animal cell The amounts of these positively-charged ions in the cell needs to stay …
Green Fluorescent Protein goes by the nickname "GFP." It was first found in jellyfish and named for its unique ability to fluoresce, or emit light, that is--you guessed it--the color green! GFP emits green light when activated by blue or UV light. GFP is made of 236 amino acids (protein building blocks) that form what …
You have more collagen in your body than any other protein. You can find it almost everywhere, but a lot of it lives in your bones, skin, and cartilage. Although collagen is made by your cells, it works outside of the cells. Collagen is a structural protein, and it is the primary protein that forms …
IgG is an abbreviation for immunoglobulin G. IgG is in the antibody family of proteins along with IgM, IgA, IgD, and IgE. Antibodies are proteins made by immune cells to recognize foreign objects in the body. They are secreted into the blood and circulated throughout the body so they can find those foreign objects. Each …
ACE2 is short for Angiotensin-Converting Enzyme 2, because it "converts" the peptide angiotensin II into angiotensin. Angiotensin II tells your body's blood vessels to get smaller which raises blood pressure, but angiotensin tells them to get larger and lowers blood pressure. In this way, ACE2's job is to lower blood pressure. ACE2 lives in the …
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